Mengo Senior School is located on Hoima Road Plot 422, Block 10. It was founded in 1895 by the Church Missionary Society (CMS). This makes it one of the oldest schools in Uganda. It is a co-educational government aided school with a current ratio of 1:2 girls to boys. It offers general academic subjects, Vocational and Technical subjects, 19 in number supported with counselling lessons, library and project work time. The school, though Church of Uganda Founded, admits students of all faiths. It provides secular education which is in line with the Uganda national goals and objectives of education. The school recognises the 21st century global trends and has always organised and re-organised its curricula to suit the needs of the changing world basing on the national curriculum.
The school was founded and is owned by Namirembe Diocese; Church of Uganda (Anglican). The Foundation body nominates 5 (five) members to the Board of Governors; one of whom is the Chairperson. The current chairman of the Foundation body is Rt. Rev. Moses Banja – Bishop of Namirembe Diocese.